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Showing 4 results for Nucleus


Volume 9, Issue 4 (12-2018)
Abstract

Aims: In nanoecotoxicology science, fish erythrocyte micronucleus assay for the monitoring genotoxic potential of nanoparticles is a powerful biomarker. This study was conducted with the aim of investigating genotoxicity of magnetic iron oxide (Fe3O4) nanoparticles in red blood cells of common carp (Cyprinus carpio) using micronucleus assay under acute and chronic treatment. Materials and Methods: In the current experimental study, the genotoxit toxicology of Fe3O4 nanoparticles was performed during an acute (96 hours; 5 concentrations including 0, 10, 100, 500, and 1000 mg/l) and chronic (14 days; 3 concentrations including 0, 100, and 500 mg/l) of Fe3O4 nanoparticles in three replications. The data were analyzed by IBM SPSS 19, using two-way ANOVA, and Duncan's new multiple range test.
Findings: Acute exposure to Fe3O4 nanoparticles had no acute toxicity effect juvenile carp (C. carpio). By increasing the concentration of nanoparticles in a 96-hour interval, the frequency of micronucleus () and other abnormal forms around the red blood cell nucleus of juvenile carps showed a significant increase compared to the control group (p<0.05). In the chronic treatment at concentrations of 100 and 500 mg/l of Fe3O4 nanoparticles, the rate of increase in the frequency of micronucleus was similar to the acute functional test of concentration.
Conclusion: Although Fe3O4 nanoparticles do not have acute toxicity effects in common carp and are non-toxic, they tend to induce genotoxic effects by increasing the frequency of micronucleus and other abnormalities of the red blood cell core during a concentration-dependent process. So, it seems that the release of FeO4NPs into the environment, it is probable adverse effects on aquatic ecosystems.

Aliyeh K.z. Kambuziya, Mehdi Zolfaghari Serish,
Volume 13, Issue 1 (1-2006)
Abstract

In Persian, the only syllable type with consonant clusters is cvcc, where its coda can be filled with two consonants. The present article attempts to find whether these two consonant conform the sonority sequencing principle or not. For this reason, the Persian words with cvcc syllable type are gathered from Persian dictionaries and are classified based on the vowel filling the nucleus of the syllables and the consonants in the first or second slot of the coda and the following results were obtained: a. Sonority sequencing principle is confirmed in clusters nuclei are /i,u,a/. b. Sonority sequencing principle is rejected in clusters with vowels /æ, e,o/. c. Based on sonority sequencing principle, vowels in Persian make up two natural classes namely / æ, e,o/ and /i,u,a/.

Volume 17, Issue 2 (6-2014)
Abstract

Objective: In the present study, we examined the effects of memantine administration within the nucleus accumbens on the alterations in brain and adrenal volumes and weight ratios induced by stress from electric foot shock. Methods: A group of mice received various doses of memantine (0.1, 0.5 and 1 mg/kg) prior to induction of stress. Another group underwent intra-accumbal cannulation after anesthesia. One week later, memantine (0.1, 0.5 and 1 µg/mouse) was injected within the nucleus accumbens prior to induction of stress. Subsequently all animals were killed. Their brains and adrenal glands were removed and fixed in 4% formalin. The volume and weight was determined by mercury immersion and method respectively. Results: The stress group showed evidence of reduction in  brain volume and weight ratio to volume, and weight of the adrenal gland. Memantine increased the ratio of the brain volume and weight to the volume and weight of the adrenal gland. Memantine administration within the nucleus accumbens also could alter this ratio. Hence, all three doses of memantine that were injected on the right side and bilateral to the nucleus inhibited the effects of stress. Conclusion: Inhibition of NMDA receptors in the nucleus accumbens can inhibit the destructive effects of chronic stress on brain volume and weight. In addition, memantine can inhibit the influence of stress on adrenal volume and weight. We have shown that this effect was both dose and injection site dependent.  In this regard, the left side of the nucleus was weaker.

Volume 31, Issue 2 (12-2024)
Abstract

   Change in the family in Iran has strengthened the discourse of disintegration. In this article examines the phenomenological study of the conceptual space of the family and its status through of actors. The research has been done with a qualitative approach and relying on the live people from different family models. The study population is a purposeful sample of 29 residents of Tehran at 2017, which includes the normative family and its alternatives. Necessary data were collected by interview technique and analyzed and interpreted by content analysis method. Research has shown that in the mental space of actors, the family model is not obsolete but is facing changes and has changed from function emotional and from rigid structure to fluid and process and jointly with the main the main themes of sexual satisfaction, support, commitment, love and Sustainability is built. Strategies show that the family and its alternatives are moving towards the nuclear family model. Also, an important feature of the family and its distinguishing feature from the Western model is maintaining family relations, navigating the kinship system, and maintaining its emotional and economic support. Thus, the dependent nuclear family is the dominant mode in the conceptual space of the family.


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